Status:
COMPLETED
Testing the Anesthetic Effectiveness of Buffered Articaine Injected Next to a Lower First Molar.
Lead Sponsor:
Ohio State University
Conditions:
Anesthetic Effectiveness
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
Infiltration (injecting next to the tooth) injections are common in dentistry and a number of studies have shown that articaine anesthetic, when injected next to a lower molar, is more effective than ...
Detailed Description
Using a crossover design, 80 adult subjects will receive two injections consisting of a primary mandibular first molar infiltration of 1.8 mL of non-buffered 4% articaine with 1:100,000 epinephrine, a...
Eligibility Criteria
Inclusion
- Between the age of 18-65 years.
- in good health (ASA classification II or higher).
- able to provide informed consent.
Exclusion
- allergy to articaine.
- history of significant medical problems (ASA classification of III or worse).
- diagnosed depression (taking tri-cyclic antidepressant medications to control).
- have taken central nervous system (CNS) depressants (including alcohol or any analgesic medications) within the last 48 hours prior to testing.
- lactating or pregnant.
- inability to give informed consent.
Key Trial Info
Start Date :
April 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2014
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT01862614
Start Date
April 1 2013
End Date
May 1 2014
Last Update
May 26 2021
Active Locations (1)
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1
The Ohio State University College of Dentistry, Postle Hall
Columbus, Ohio, United States, 43210