Status:
UNKNOWN
The Effect of Ulinastatin on Bronchoalveolar Lavage Fluid of Inflammatory Factors in Patients With Ventilator-associated Pneumonia
Lead Sponsor:
Shanghai Minhang Central Hospital
Collaborating Sponsors:
Ruijin Hospital
RenJi Hospital
Conditions:
Ventilator-associated Bacterial Pneumonia
Mechanical Ventilation Complication
Eligibility:
All Genders
18-80 years
Phase:
PHASE2
PHASE3
Brief Summary
Ventilator-associated pneumonia (VAP) is an important cause of morbidity and mortality in ventilated critically ill patients specially in intensive care unit (ICU). It is associated with an increased ...
Detailed Description
This is a one-center, three-arm, randomized, single-blinded, controlled trial. When a patient was diagnosed VAP during mechanic ventilation in ICU,a sealed envelop will be opened which decide whether ...
Eligibility Criteria
Inclusion
- All consecutive patients with ventilator-associated pneumonia(VAP) who are admitted to the intensive care unit between 1st January 2014 at 0:00(midnight) and the finish date of 31st December 2015 at 23:59 (11:59 pm).
- Informed consent.
Exclusion
- Patients with pneumonia when they are admitted to ICU.
- Ulinastatin was previous used before the patients were diagnosed VAP.
- Active gastropathic disorder.
- Be allergic to ulinastatin.
- Pregnancy.
- Unwilling to continue the therapy during hospitalization.
Key Trial Info
Start Date :
January 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2016
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01865266
Start Date
January 1 2014
End Date
June 1 2016
Last Update
May 30 2013
Active Locations (1)
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1
Shanghai Minhang Central Hospital
Shanghai, China, 201199