Status:
COMPLETED
Adaptation to Living With a BRCA1/2 Mutation
Lead Sponsor:
National Human Genome Research Institute (NHGRI)
Collaborating Sponsors:
Johns Hopkins Bloomberg School of Public Health
Conditions:
Cancer Genetics
Eligibility:
All Genders
18+ years
Brief Summary
Background: \- Women who have a BRCA1/2 gene mutation have a very high risk of developing breast or ovarian cancer. They are also at increased risk of other developing other cancers. Male carriers ar...
Detailed Description
The proposed study aims to describe adaptation and dyadic adjustment in unaffected BRCA1/2 carriers and their partners. It is not fully understood how women and their partners adapt to highrisk status...
Eligibility Criteria
Inclusion
- INCLUSION AND EXCLUSION CRITERIA:
- Participants will be women aged 18 or older who have a BRCA1/2 mutation and their (male or female) partners. Carriers must have no personal history of cancer, but partners will not be excluded based on cancer history. Participants will be asked to disclose their mutation status (BRCA1 or BRCA2), but no screening evaluation will be required. If only one member of a couple completes the survey, their data will be included in the individual level analysis, but excluded from the dyadic level analysis.
Exclusion
Key Trial Info
Start Date :
May 2 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 20 2014
Estimated Enrollment :
142 Patients enrolled
Trial Details
Trial ID
NCT01866865
Start Date
May 2 2013
End Date
February 20 2014
Last Update
April 5 2018
Active Locations (1)
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1
Johns Hopkins Bloomberg School of Public Health
Baltimore, Maryland, United States