Status:
TERMINATED
ACE-Inhibitor Effects on Total Hip and Knee Arthroplasty Patients
Lead Sponsor:
Duke University
Conditions:
Adverse Effects of Angiotensin-converting-enzyme Inhibitors
Hypotension
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to determine the effects of Angiotension Converting Enzyme Inhibitors (ACE-I) during surgery and in the immediate postoperative period for patients undergoing elective tot...
Eligibility Criteria
Inclusion
- Patients electing to undergo primary or revision total hip or knee arthroplasty
- Currently taking an ACE-I
Exclusion
- Trauma patients
- Immunosuppressed patients (HIV/AIDS, organ transplant recipients, chemotherapy patients, chronic steroid use)
- Patients with history of severe hypertension related illness such as hypertension associated with stroke or myocardial infarction
- Patients in who continuation of their ACE-I is expressly mandated by their prescribing physician
Key Trial Info
Start Date :
June 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 24 2016
Estimated Enrollment :
59 Patients enrolled
Trial Details
Trial ID
NCT01867047
Start Date
June 1 2013
End Date
June 24 2016
Last Update
September 28 2017
Active Locations (1)
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1
Duke University
Durham, North Carolina, United States, 27710