Status:
TERMINATED
Early Markers of Alzheimer's Disease: Structural and Functional Brain Changes
Lead Sponsor:
National Institute on Aging (NIA)
Collaborating Sponsors:
Johns Hopkins University
Conditions:
Alzheimer's Disease
Eligibility:
All Genders
20+ years
Brief Summary
Background: \- Participants in the Baltimore Longitudinal Study of Aging are being studied to examine changes in brain structure and function over time, and to determine if these changes can predict ...
Detailed Description
We are examining changes in brain structure and function as predictors of cognitive decline and impairment through longitudinal neuroimaging assessments of selected Baltimore Longitudinal Study of Agi...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- BLSA participants who do not meet exclusion criteria
- EXCLUSION CRITERIA:
- Miscellaneous: Body weight \> 300 pounds, history of significant radiation exposure.
- Participants with pacemakers, implanted electronic hearing devices, aneurysm clips, shrapnel, unallowed prosthetic or any other metallic device in their bodies.
- Pre-existing CNS disease or severe cardiovascular disease (MI, CABG, angioplasty).
Exclusion
Key Trial Info
Start Date :
March 10 2003
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 22 2014
Estimated Enrollment :
213 Patients enrolled
Trial Details
Trial ID
NCT01867372
Start Date
March 10 2003
End Date
September 22 2014
Last Update
December 12 2019
Active Locations (3)
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1
Johns Hopkins University
Baltimore, Maryland, United States, 21205
2
Kennedy Krieger Institute
Baltimore, Maryland, United States, 21205
3
National Institute of Aging, Clinical Research Unit
Baltimore, Maryland, United States, 21224