Status:
COMPLETED
Study of Lung Health Among Workers Exposed to Diesel Exhaust
Lead Sponsor:
National Cancer Institute (NCI)
Collaborating Sponsors:
Utrecht University
Boston University
Conditions:
Inflammation Biomarkers
mRNA Expression
Eligibility:
All Genders
18-70 years
Brief Summary
Background: \- Diesel fuel is the most commonly used fuel to power cars and trucks worldwide. However, diesel exhaust fumes can have harmful effects on the body. Researchers are interested in studyin...
Detailed Description
The Occupational and Environmental Epidemiology Branch has a long history of conducting research on the carcinogenicity of diesel exhaust exposure. Most recently, a 20 year effort in collaboration wit...
Eligibility Criteria
Inclusion
- INCLUSION:
- Inclusion criteria for workers exposed to diesel exhaust:
- To be current workers in the diesel engine testing facility of a study factory in the selected region of China. All workers in this facility are male.
- Inclusion criteria for workers not exposed to diesel exhaust (controls):
- To be a current male worker in a selected control study factory, that does not have exposure to diesel exhaust or other types of particulates, or any known or suspected genotoxic, hematotoxic, or immunotoxic chemicals, who is comparable to workers working in the diesel engine testing facility by age and smoking status .
- EXCLUSION CRITERIA:
- None.
Exclusion
Key Trial Info
Start Date :
March 28 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 12 2020
Estimated Enrollment :
109 Patients enrolled
Trial Details
Trial ID
NCT01867450
Start Date
March 28 2013
End Date
November 12 2020
Last Update
November 13 2020
Active Locations (1)
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1
Chinese Center for Disease Control & Prevention
Beijing, China