Status:
COMPLETED
Study of Metformin Pharmacogenetics in Twins
Lead Sponsor:
University of Southern Denmark
Conditions:
Type 2 Diabetes
Eligibility:
All Genders
18-40 years
Phase:
PHASE1
Brief Summary
The trough concentration of metformin will be examined in monozygotic and dizygotic twins. Current twin study will determine the total weight of genetics on the trough concentration of metformin.
Eligibility Criteria
Inclusion
- Age 18-40 years
- Both twins has to be included
- Dizygotic twin pairs has to be same sex
- Informed consent given
- Healthy condition
Exclusion
- Chronical/daily alcohol abuse
- Hypersensitivity to metformin
- Ingestion of drugs containing topiramate or x-ray contrast fluids
- For women: Positive pregnancy test/breastfeeding at the beginning of the trial. No use of safe anticonceptives
Key Trial Info
Start Date :
April 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2014
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT01869621
Start Date
April 1 2013
End Date
October 1 2014
Last Update
December 3 2014
Active Locations (1)
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1
Clinical Pharmacology
Odense C, Denmark, 5000