Status:
COMPLETED
A Comparison of Propofol Based Total Intravenous Anesthesia and Desflurane Based Balanced Anesthesia on Renal Protection During Deceased Brain Dead Donor Kidney Transplantation - A Prospective, Randomized Trial
Lead Sponsor:
Yonsei University
Conditions:
End Stage Renal Disease
Eligibility:
All Genders
20-69 years
Phase:
PHASE4
Brief Summary
Renal ischemia/reperfusion (I/R)-induced injury is known to be associated with immediate and long-term kidney dysfunction after renal transplantation. Protecting the kidney against I/R injury and main...
Eligibility Criteria
Inclusion
- Adult deceased brain dead kidney donors and recipients scheduled for renal transplantation
Exclusion
- 1\. Donor exclusion criteria:
- (1) Refusal of legal guardian
- 2\. Recipient exclusion criteria:
- Patient refusal
- Hypersensitivity to propofol, soybeans or peanuts
- History of vitamin C or E intake within 5 days before surgery
- History of acute myocardial infarct within 6 months before surgery
- Congestive heart failure (NYHA III-IV)
- Autoimmune disease patients
- BMI over 30 kg/m2
- Left ventricular ejection fraction less than 35% upon preoperative echocardiography
Key Trial Info
Start Date :
December 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2014
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT01870011
Start Date
December 1 2013
End Date
November 1 2014
Last Update
August 17 2016
Active Locations (1)
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1
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine
Seoul, Seoul, South Korea, 120-752