Status:
COMPLETED
Atorvastatin Versus Rosuvastatin on Contrast Induced Acute Kidney Injury (PRATO-ACS 2)
Lead Sponsor:
Centro Cardiopatici Toscani
Conditions:
Acute Coronary Syndrome
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The aim of the project is to compare the nephro-protective effects of high-dose atorvastatin and high-dose rosuvastatin on the incidence of Contrast Induced-Acute Kidney Injury in patients with non-ST...
Detailed Description
This is a prospective, single-centre, randomized study, designed to compare the nephro-protective effects of high-dose atorvastatin and high-dose rosuvastatin on the incidence of Contrast Induced-Acut...
Eligibility Criteria
Inclusion
- All consecutive statin-naive patients with non ST-elevation acute coronary syndrome admitted to our institution and scheduled for early invasive strategy are considered for enrollment
Exclusion
- Current statin treatment
- High-risk features warranting emergency coronary angiography (within 2 hours)
- Acute renal failure or end-stage renal failure requiring dialysis or serum creatinine ≥ 3 mg/dl
- Severe comorbidities which precluded early invasive strategy
- Contraindications to statin treatment
- Contrast media administration within the last 10 days
- Pregnancy
- Refusal of consent
Key Trial Info
Start Date :
May 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2016
Estimated Enrollment :
760 Patients enrolled
Trial Details
Trial ID
NCT01870804
Start Date
May 1 2013
End Date
September 1 2016
Last Update
October 6 2016
Active Locations (1)
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1
Cardiology Division, Prato Hospital
Prato, Prato, Italy, 59100