Status:

COMPLETED

Identification of Null Allelic Variant of CYP2C8 In A Korean Population

Lead Sponsor:

Inje University

Conditions:

Healthy

Eligibility:

All Genders

20-65 years

Phase:

PHASE1

Brief Summary

The genotype profile of CYP2C8 was analyzed in a Korean population. Frequency in multi-ethnic population and in vivo functionality of novel null allelic CYP2C8 variant were evaluated.

Detailed Description

Whole blood samples from 50 unrelated Korean subjects were genotyped for 3kb of 5' upstream region, all exon-intron boundaries, exons, and UTR regions of CYP2C8 gene by direct sequencing. Genotyping o...

Eligibility Criteria

Inclusion

  • Healthy volunteer

Exclusion

  • Medical problems in taking probe drug

Key Trial Info

Start Date :

August 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2009

Estimated Enrollment :

11 Patients enrolled

Trial Details

Trial ID

NCT01872780

Start Date

August 1 2008

End Date

March 1 2009

Last Update

June 7 2013

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