Status:
UNKNOWN
Transplantation of Bone Marrow Mesenchymal Stem Cell in Crohn's Disease
Lead Sponsor:
Royan Institute
Conditions:
Crohn's Disease
Eligibility:
All Genders
18-65 years
Phase:
PHASE1
Brief Summary
This study is a prospective, randomized, parallel, phase 1 trial to assess the safety and feasibility of the transplantation of bone marrow derived mesenchymal stem cells (MSCs) in fistulizing Crohn's...
Detailed Description
In this study all eligible patients were randomly allocated into two study groups by a permuted block randomization method: group A receives only autologous MSCs suspended in fibrin glue, group B rece...
Eligibility Criteria
Inclusion
- 1- Poor response to routine treatments in refractory Crohn's disease with fistula.
- 2- CDAI\>220 3- Age 18 to 60 years 4- GFR\>30, Cr\<2 5- The presence of perinea fistula.
Exclusion
- pregnancy
Key Trial Info
Start Date :
February 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2018
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT01874015
Start Date
February 1 2013
End Date
February 1 2018
Last Update
April 27 2017
Active Locations (1)
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1
Royan Institute
Tehran, Iran