Status:

COMPLETED

Effect of Anti-inflammatory Diet on Inflammatory, Oxidative and Nutritional Markers in Hemodialysis Patients

Lead Sponsor:

Maryam Ekramzadeh, PhD

Collaborating Sponsors:

Shiraz University of Medical Sciences

Conditions:

Inflammation

Malnutrition

Eligibility:

All Genders

18-85 years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate the effect of especial diet therapy "Anti-inflammatory Diet" on inflammatory, oxidative stress, and nutritional markers in the context of protein-energy wastin...

Eligibility Criteria

Inclusion

  • Patients who are on hemodialysis(HD) at least two times a week for 3months or more without any internment illness or admission

Exclusion

  • Hospitalization because of sepsis or surgery 3 months prior to intervention
  • Cirrhosis
  • Hepatitis virus infection
  • Human Immunodeficiency virus infection
  • Acquired Immunodeficiency Syndrome
  • Active malignancy
  • Active infection
  • Absence of communication
  • Mental Impairment
  • Terminal illness
  • Tube feedings
  • Total parenteral nutrition
  • Pregnancy
  • Not previously seen by a dietitian within 3 months prior to enrollment in the study
  • Not expected to be transplanted within 6 months after the enrollment in the study
  • Absence of malnutrition from a cause other than end stage renal disease(ESRD)
  • Psychiatric conditions, preventing adherence to intervention
  • Consuming immunosuppressive drugs or taking antioxidant supplements including Vitamin E, Vitamin C, N-acetyl- cysteine (NAC), Pentoxifylline, Lipoic acid,Fish-oil extracts (omega-3 fatty acids), Soy extracts(isoflavones), Green-tea preparations, Pomegranate extracts, Grape extracts within 2 months prior to enrollment in the study

Key Trial Info

Start Date :

October 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2013

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT01874106

Start Date

October 1 2012

End Date

August 1 2013

Last Update

January 8 2014

Active Locations (1)

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Shiraz University of Medical Sciences, Department of Nutrition

Shiraz, Fars, Iran