Status:

COMPLETED

Study on Colonic Fermentation in Chronic Kidney Disease Patients

Lead Sponsor:

Universitaire Ziekenhuizen KU Leuven

Conditions:

Renal Insufficiency, Chronic

Eligibility:

All Genders

18-95 years

Brief Summary

Chronic kidney disease is associated with the accumulation of various metabolites, i.e., uremic retention solutes. Evidence is mounting that the colonic microbiome contributes substantially to these u...

Eligibility Criteria

Inclusion

  • Age ≥ 18 and ≤ 95 years
  • Treatment with renal replacement therapy, i.e. hemo- or peritoneal dialysis for more than 3 months
  • Written informed consent

Exclusion

  • History of organic gastro-intestinal disease (e.g., inflammatory bowel disease, malignancy)
  • History of colonic surgery
  • Recipient of a renal or other solid organ transplant
  • Use of pre-/pro-/syn- or antibiotics in preceding 4 weeks

Key Trial Info

Start Date :

February 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 1 2016

Estimated Enrollment :

65 Patients enrolled

Trial Details

Trial ID

NCT01874210

Start Date

February 1 2008

End Date

May 1 2016

Last Update

May 18 2016

Active Locations (1)

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1

University Hospitals Leuven

Leuven, Vlaams-Brabant, Belgium, 3000