Status:

UNKNOWN

Use of Transcollation Device to Decrease Blood Loss During Hepatic Resections: a Randomized Cohort Study (HEPACOLL)

Lead Sponsor:

University Hospital, Clermont-Ferrand

Collaborating Sponsors:

INNOPATH

MEDTRONIC labs provide the aquamantys® probes for the study.

Conditions:

Hepatectomy

Eligibility:

All Genders

18-80 years

Phase:

PHASE2

Brief Summary

Blood loss in hepatic surgery is the main factor of postoperative morbidity. The use of the most effective possible tool for hemostasis allows a bleeding decrease during liver transection and thus cou...

Detailed Description

After validation of the inclusion and exclusion criteria, the patients include in this clinical trial will be randomized between the two arms of the study: * Control group: hepatectomy with conventio...

Eligibility Criteria

Inclusion

  • Patients undergoing elective surgery for liver resection of malignant or benign disease
  • Hepatic resection of two or more segments
  • No coagulation disorder
  • No portal hypertension (platelets ≥ 100 G/L, absence of splenomegaly, absence of portal hypertension varices)
  • Obtaining the patient's written consent

Exclusion

  • Age \< 18 years and \> 80 years
  • ASA score \> 3
  • Cirrhosis, liver fibrosis \> F2, steatosis \> 60%, sinusoidal obstruction syndrome
  • Cognitive troubles and major disability making impossible to understand the study and signed the informed consent (e.g. dementia, psychiatric disorders like psychosis, speech disorder ...)
  • Liver and kidney failure
  • Pregnancy and lactating women
  • Legal incapacity
  • Patients already enrolled in a clinical trial

Key Trial Info

Start Date :

June 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2016

Estimated Enrollment :

140 Patients enrolled

Trial Details

Trial ID

NCT01874639

Start Date

June 1 2013

End Date

December 1 2016

Last Update

July 29 2016

Active Locations (1)

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CHU Clermont-Ferrand

Clermont-Ferrand, France, 63003