Status:
COMPLETED
Biomarker Identification in Orthopaedic & Oral Maxillofacial Surgery Subjects to Identify Risks of Bisphosphonate Use
Lead Sponsor:
University of Pennsylvania
Conditions:
Osteoporosis, With or Without Treatment
Bisphosphonate Treatment
Eligibility:
All Genders
18+ years
Brief Summary
Bisphosphonates are drugs that prevent bone loss by blocking the activity of cells that normally resorb bone. The most common examples of these drugs are Boniva and Fosamax. These drugs are available ...
Detailed Description
Collected specimens were subjected to Affymetrix DMET™ Plus Solution analysis. Manuscript is in preparation.
Eligibility Criteria
Inclusion
- Any adult (male or female) age 18 or over meeting any of the following criteria:
- All participants must be able to provide informed consent for themselves.
- History of BP treatment with or without BRONJ and/or Femur fracture (typical or atypical)
- No History of BP treatment with or without BRONJ and/or Femur fracture (typical or atypical)
Exclusion
- Children age 17 or younger
- Adults who cannot or do not make medical decisions for themselves
- Persons known to be under the jurisdiction of the Department of Corrections
- Individuals who are pregnant.
Key Trial Info
Start Date :
April 13 2012
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 30 2022
Estimated Enrollment :
314 Patients enrolled
Trial Details
Trial ID
NCT01875458
Start Date
April 13 2012
End Date
October 30 2022
Last Update
January 13 2023
Active Locations (1)
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1
University of Pennsylvania Health System
Philadelphia, Pennsylvania, United States, 19104