Status:
COMPLETED
Effect of Phytosterols on Nonalcoholic Fatty Liver Disease
Lead Sponsor:
China Medical University Hospital
Conditions:
Non-alcoholic Fatty Liver Disease
Eligibility:
All Genders
25-80 years
Phase:
NA
Brief Summary
Phytosterols are plant sterols . Phytosterols have anti-inflammation effect. Investigators have a hypothesis: phytosterols reduce oxidative stress , enhance Insulin-like growth factor-1(IGF-1) and end...
Detailed Description
Fatty liver is the hepatic feature of metabolic syndrome. Metabolic syndrome increase the risk of atherosclerosis and cardiovascular disease. Adipose tissue secrete adipocytes accumulate in the liver ...
Eligibility Criteria
Inclusion
- (1)25-80 years
- (2)Fatty liver was diagnosed by abdominal echo by the same gastrologist, review by another gastrologist
Exclusion
- (1)Serological markers of hepatitis B virus(hepatitis B surface antigen and anti-HBs antibody) and hepatitis C virus infection (anti-HCV antibody)
- (2)Autoimmune liver disease or alcoholic liver disease(alcohol intake more than 20g per day by using a questionnaire)
- (3)Malignant diseases
- (4)Pregnancy or breast feeding
- (5)Clinical evidence of angina, congestive heart failure, valvular heart disease, inflammatory disease or thyroid dysfunction
Key Trial Info
Start Date :
October 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2013
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT01875978
Start Date
October 1 2012
End Date
July 1 2013
Last Update
June 11 2014
Active Locations (1)
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1
China Medical University Hospital
Taichung, Taiwan