Status:

COMPLETED

Dexamethasone and Ondansetron Versus Placebo for Postoperative Nausea and Vomiting

Lead Sponsor:

Hopital Foch

Conditions:

Postoperative Nausea and Vomiting

Eligibility:

All Genders

18-75 years

Phase:

PHASE4

Brief Summary

The investigators want to test if it is indicated to associate dexamethasone and ondansetron in obese patients having bariatric surgery under total intra-venous closed-loop anesthesia.

Detailed Description

Obese patients having bariatric surgery have frequently postoperative nausea and vomiting (PONV). We want to test if it is indicated to associate dexamethasone and ondansetron in obese patients having...

Eligibility Criteria

Inclusion

  • Adult patients aged 18-75 years
  • Scheduled for bariatric surgery under total intra-venous closed-loop anesthesia
  • Apfel score equal or greater than 2
  • Consenting to participate in the study

Exclusion

  • Pregnant, breast feeding women
  • Allergy
  • Contraindication to dexamethasone
  • Contraindication to ondansetron
  • Contraindication to propofol, remifentanil, morphine, ketoprofen
  • Limit to the use of bispectral index

Key Trial Info

Start Date :

May 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2015

Estimated Enrollment :

122 Patients enrolled

Trial Details

Trial ID

NCT01876290

Start Date

May 1 2013

End Date

March 1 2015

Last Update

October 31 2016

Active Locations (1)

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Clinique de la Baie des Citrons

Nouméa, France, 98800