Status:
COMPLETED
Color Vision as a Measure for Inherited Retinal Diseases
Lead Sponsor:
National Eye Institute (NEI)
Conditions:
Healthy Volunteer
Retinal Disease
Eligibility:
All Genders
5+ years
Brief Summary
Background: \- The purpose of this study is to find out whether color vision measured with the Cambridge Color Test is a good way to examine the severity of inherited retinal diseases (IRDs). IRDs ar...
Detailed Description
Objective: The aims of this study are to 1) examine the sensitivity of the Cambridge Color Test (CCT) and the low vision CCT (LvCCT) to the severity of retinal disease in inherited retinal degeneratio...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Participants must be 5 years of age or older.
- Participant (or legal guardian) must understand and sign the protocol s informed consent document.
- Participant must be able to cooperate with the testing required for this study.
- Participant s eyes must have clarity of ocular media and degree of pupil dilation sufficient to permit adequate fundus photography.
- For IRD Participants only:
- Participant must have IRD, defined as evidence of retinal rod- and cone-mediated
- dysfunction and degeneration established by standard clinical methods including field tests, ERG, and imaging.
- Participant must have a measurable visual acuity.
- For Healthy Volunteers only:
- Participant must have visual acuity of 20/20 or better.
- EXCLUSION CRITERIA:
- Participant is taking medications known to alter color vision, such as hydroxychloroquine (Plaquenil ), sildenafil (Viagra ), ethambutol, chloroquine amiodarone, and pamidronate disodium.
- Participant has another ocular disease that may confound the study results, such as diabetic retinopathy, vascular occlusions, retinopathy related to drug toxicity, optic neuropathy, or central serous chorioretinopathy.
Exclusion
Key Trial Info
Start Date :
June 3 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 14 2017
Estimated Enrollment :
166 Patients enrolled
Trial Details
Trial ID
NCT01878032
Start Date
June 3 2013
End Date
April 14 2017
Last Update
October 6 2017
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892