Status:

COMPLETED

Safety and Efficacy of Vilazodone in Adolescent Patients With Major Depressive Disorder

Lead Sponsor:

Forest Laboratories

Conditions:

Major Depressive Disorder

Eligibility:

All Genders

12-17 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to evaluate the efficacy, safety, and tolerability of vilazodone relative to placebo in adolescent outpatients (12-17) with major depressive disorder.

Eligibility Criteria

Inclusion

  • Male or Female outpatients between 12-17 years of age
  • Primary diagnosis of major depressive disorder (MDD)
  • Children's Depression Rating Scale-Revised (CDRS-R) score of 40 or greater
  • Clinical Global Impressions-Severity (CGI-S) score of 4 or greater

Exclusion

  • Current (past 3 months) principal Diagnostic and Statistical Manual of Mental Disorders, 4th edition, Text Revision (DSM-IV-TR) based diagnosis of an axis disorder other than major depressive disorder (MDD) that is the primary focus of treatment.
  • History of suicidal behavior, or requires precaution against suicide
  • Not generally healthy medical condition
  • Seizure disorder

Key Trial Info

Start Date :

July 11 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 5 2016

Estimated Enrollment :

529 Patients enrolled

Trial Details

Trial ID

NCT01878292

Start Date

July 11 2013

End Date

October 5 2016

Last Update

December 24 2019

Active Locations (52)

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Page 1 of 13 (52 locations)

1

Forest Investigative Site 073

Imperial, California, United States, 92251

2

Forest Investigative Site 052

Los Angeles, California, United States, 90027

3

Forest Investigative Site 023

Murrieta, California, United States, 92562

4

Forest Investigative Site 004

Orange, California, United States, 92868