Status:
COMPLETED
A Study to Help People Quit Smoking.
Lead Sponsor:
Yale University
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Nicotine Dependence
Eligibility:
All Genders
18-55 years
Phase:
NA
Brief Summary
You are invited to participate in a research study at the VA Connecticut Healthcare System (West Haven campus) that examines whether a medication called galantamine can improve your learning and memor...
Detailed Description
We propose a double-blind, placebo-controlled, outpatient study with a between-groups design. Seventy-two male and female smokers will be randomly assigned to one of the 3 treatment conditions: GAL (8...
Eligibility Criteria
Inclusion
- Female and male smokers, aged 18 to 55 years;
- history of smoking daily for the past 12 months, at least 10 cigarettes daily;
- in good health as verified by medical history, screening examination, and screening laboratory tests;
- for women, not pregnant as determined by pregnancy screening, nor breast feeding, and using acceptable birth control methods.
Exclusion
- History of GAL allergy;
- requirement of any form of regular psychotropic medication (antidepressants, antipsychotics, or anxiolytics) and recent psychiatric history (in the past 6 months);
- serious medical illness including asthma, diabetes, bradycardia, or other arrhythmias and major cardiovascular, renal, endocrine, or hepatic disorders;
- abuse of alcohol or any other illicit or prescription drugs;
- use of any other tobacco products, including smokeless tobacco and nicotine products; and
- inability to fulfill all scheduled visits and examination procedures throughout the study period.
Key Trial Info
Start Date :
December 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2015
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01880099
Start Date
December 1 2013
End Date
December 1 2015
Last Update
March 23 2020
Active Locations (1)
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1
Veteran Affairs
West Haven, Connecticut, United States, 06516