Status:

COMPLETED

A Study to Assess if Scratching the Lining of the Womb Prior to IVF Treatment Increases the Chances of Pregnancy

Lead Sponsor:

Nottingham University Hospitals NHS Trust

Collaborating Sponsors:

University of Nottingham

University Hospitals Coventry and Warwickshire NHS Trust

Conditions:

Infertility

Eligibility:

FEMALE

18-49 years

Phase:

PHASE2

PHASE3

Brief Summary

This study aims to see if taking a small sample from the lining of the womb (the 'scratch') before starting in vitro fertilization (IVF) treatment can influence the chance of getting pregnant and havi...

Detailed Description

Following consent, participants will be randomised to one of the two trial interventions (endometrial biopsy, or ultrasound scan only = no intervention) by a member of the research team. The procedure...

Eligibility Criteria

Inclusion

  • Women with history of primary or secondary infertility undergoing fresh IVF/ ICSI treatment or frozen embryo replacement cycle
  • Age \<49

Exclusion

  • Non- ovulatory cycles
  • Absent uterus
  • Uterine instrumentation within previous 3 menstrual cycles
  • Women in the oocyte donation program

Key Trial Info

Start Date :

February 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2015

Estimated Enrollment :

160 Patients enrolled

Trial Details

Trial ID

NCT01882842

Start Date

February 1 2013

End Date

June 1 2015

Last Update

November 22 2016

Active Locations (1)

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Nurture Fertility

Nottingham, Nottinghamshire, United Kingdom, NG7 2UH