Status:
COMPLETED
Effect of Aerobic Interval Training on Cardiovascular Function in Type 2 Diabetes
Lead Sponsor:
University of Florida
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Type 2 Diabetes
Eligibility:
All Genders
30-79 years
Phase:
NA
Brief Summary
The study objectives are: 1. To compare cardiovascular function in type 2 diabetes patients vs. healthy controls. 2. To compare the effect of 8 weeks of aerobic interval training versus continuous mo...
Detailed Description
Cardiovascular function will be measured at baseline in adults with type 2 diabetes and in age-matched healthy controls. Research volunteers with type 2 diabetes who meet the inclusion criteria will b...
Eligibility Criteria
Inclusion
- Inclusion Criteria for type 2 diabetes :
- Diagnosis of type 2 diabetes
- Sedentary or minimally physically active for at least the prior 1 year
- Able to give consent
- Inclusion criteria for healthy control group:
- Sedentary or minimally physically active for at least the prior 1 year
- Able to give consent
- Exclusion Criteria:
- History of diabetic proliferative retinopathy, autonomic or peripheral neuropathy
- History of any relevant cardiovascular diseases (myocardial infarction, angina pectoris, history of coronary artery bypass surgery or angioplasty, congestive heart failure, or arrhythmia)
- Hypertension (≥160 mmHg systolic or ≥100 mmHg diastolic)
- History of renal impairment
- History of gout or hyperuricemia
- History of hepatic disease or infection with hepatitis B, C
- History of seizures, or other relevant on-going or recurrent illness
- Recent (within 3 months) or recurrent hospitalizations
- Use of tobacco products
- \>5 % weight change in the prior 6 months.
- Current intake of medications that may affect study results
- Premenopausal women taking oral contraceptives and postmenopausal women taking hormone replacement therapy.
- Pregnancy (positive urine pregnancy test) or lactation
- For the healthy control group, history of diabetes.
Exclusion
Key Trial Info
Start Date :
May 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 16 2018
Estimated Enrollment :
116 Patients enrolled
Trial Details
Trial ID
NCT01883258
Start Date
May 1 2013
End Date
July 16 2018
Last Update
December 6 2019
Active Locations (1)
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1
University of Florida
Gainesville, Florida, United States, 32611