Status:
COMPLETED
Pilot Trial of Opioid Taper Support
Lead Sponsor:
University of Washington
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Chronic Non-cancer Pain
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The proposed research will develop, demonstrate the feasibility of, and pilot test in a randomized controlled trial a prescription opioid taper support intervention. This intervention aims to prevent ...
Eligibility Criteria
Inclusion
- age 18-80 years;
- CNCP, defined as pain on more than half the days in the past six months, where indicated diagnostic workup is complete and treatment is focused on pain;
- currently on COT, defined as self-report of prescribed oral opioid medication use on a daily or near-daily (\>90% of days) basis for 90 days or more;
- mean daily opioid dose in the past 30 days of 25 mg MED or greater;
- willing to participate in the study arm to which they are randomly assigned (including opioid taper in-person sessions if randomized to that group);
- able to read, speak, and write English.
Exclusion
- currently receiving treatment for cancer (other than non-melanoma skin cancer);
- medical comorbidity with life expectancy less than a year (based on medical record review by the PI);
- recent use (past month) of parenteral, transdermal, or transmucosal opioids,
- currently residing in nursing home;
- currently using intrathecal pump for pain control;
- any current substance abuse according to the DSM-IV checklist (nicotine and marijuana will be allowed since Washington State allows medical marijuana for pain control);
- presence of illicit drug metabolite in baseline urine drug test,
- psychotic symptoms, psychiatric hospitalization or suicide attempts in the past year;
- current suicidal ideation with specific plan or intent;
- significant cognitive impairment (on 6-item screener Scale).
Key Trial Info
Start Date :
June 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2016
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT01883882
Start Date
June 1 2013
End Date
June 1 2016
Last Update
October 24 2016
Active Locations (1)
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1
University of Washington Center for Pain Relief
Seattle, Washington, United States, 98115