Status:

COMPLETED

Prevalence of Histoplasmosis in HIV + Patients with a Rapid Diagnostic Test in West Indies

Lead Sponsor:

ANRS, Emerging Infectious Diseases

Conditions:

HIV

Eligibility:

All Genders

18+ years

Brief Summary

Histoplasma capsulatum var. capsulatum histoplasmosis is the leading cause of acquired immunodeficiency syndrome (AIDS) and death in French Guiana and probably in the Amazon. The diagnosis of this dis...

Eligibility Criteria

Inclusion

  • Adult (aged 18 or over).
  • Patient seen while hospitalized or in outpatient awaiting hospitalization.
  • HIV1 or HIV2 infection confirmed by techniques validated in France and in Suriname, either before the episode considered, or discovered concomitantly.
  • Patient presenting at least one of the three followings items: an alteration of their general condition (with a grade 1 according to the WHO Performance Status scale) and/or a fever and/or symptoms suggestive of an infectious syndrome.
  • Medical prescription for the collection of blood and urine specimens to test for an infectious agent within 7 days following admission to the hospital.
  • Written consent to participate in the study obtained.

Exclusion

  • Refusal to participate in the study.
  • Patient in a critical condition that doesn't allow physicians to get an informed consent without a legal representative to represent him and sign a consent form for the patient participation in the study.
  • Ongoing antifungal treatment or antifungal treatment stopped during the month preceding the inclusion date (topic antifungal therapy not considered at this point).
  • Patient in detention at the time of admission to the hospital.

Key Trial Info

Start Date :

August 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 3 2015

Estimated Enrollment :

727 Patients enrolled

Trial Details

Trial ID

NCT01884779

Start Date

August 1 2013

End Date

November 3 2015

Last Update

September 3 2024

Active Locations (7)

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Page 1 of 2 (7 locations)

1

Pointe-à-Pitre University Hospital

Pointe à Pitre, Guadeloupe, France, 97159

2

Cayenne General Hospital

Cayenne, Guyane, France, 97306

3

Western French Guiana Hospital

Saint-Laurent-du-Maroni, Guyane, France, 97320

4

Fort-de-France University Hospital

Fort-de-France, Martinique, France, 97261