Status:
COMPLETED
Evaluation of Preimplantation Portal Vein and Hepatic Artery Flushing With Tacrolimus
Lead Sponsor:
Republican Scientific and Practical Center for Organ and Tissue Transplantation
Conditions:
Early Allograft Dysfunction
Ischemic Reperfusion Injury
Eligibility:
All Genders
18-69 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether the Tacrolimus added to histidine-tryptophan-ketoglutarate (HTK) solution given through intraportal and intraarterial infusion during back-table proce...
Detailed Description
Early allograft liver dysfunction remains a significant complication of cadaveric liver transplantation with resource consuming and costly treatment, increased risk of multiorgan failure and 6-months ...
Eligibility Criteria
Inclusion
- Donor:
- age 15-65 years macrovesicular steatosis \< 40% (macroscopy or biopsy) sodium \<165 mmol/l ICU stay and ventilation \< 11 days cold ischemia time \< 13 hours AST \< 200 U/l ALT \< 200 U/l bilirubin \< 50 μmol/l application of norepinephrine is allowed
- Recipient age: 18-69
Exclusion
- Recipient:
- live donor liver transplant
- reduced and split grafts
- multi organ failure
Key Trial Info
Start Date :
July 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2014
Estimated Enrollment :
86 Patients enrolled
Trial Details
Trial ID
NCT01887171
Start Date
July 1 2013
End Date
July 1 2014
Last Update
February 23 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
RSPC for organ and tissue transplantation, Minsk 9th clinic
Minsk, Belarus, 220116