Status:
COMPLETED
Penthrox Versus Tramadol for SCDF
Lead Sponsor:
Singapore General Hospital
Conditions:
Acute Pain
Eligibility:
All Genders
16+ years
Phase:
PHASE4
Brief Summary
Introduction Current practice in Singapore Emergency Ambulance Service (EAS) includes the use of analgesia delivered via inhalation Enthanox (Nitrous Oxide). However there are difficulties administer...
Detailed Description
Introduction Current practice in Singapore Emergency Ambulance Service (EAS) includes the use of analgesia delivered via inhalation Enthanox (Nitrous Oxide). However there are difficulties administer...
Eligibility Criteria
Inclusion
- Patients with acute pain, with pain score greater than 3, presenting with musculo-skeletal trauma (limbs or back) pain are eligible
- Conscious, haemodynamically stable condition (BP greater than 90/60)
- Age more than 16 years old
Exclusion
- General
- Females who are nursing or with a positive pregnancy test (pregnant)
- Patients with major head injury or impaired consciousness
- Acute intoxication with drugs or alcohol, or other conditions that might impair ability to score pain
- Chronic pain requiring ongoing use of analgesics
- Abdominal or chest pain (for the purpose of this initial implementation study)
- Penthrox only
- Known pre-existing renal or hepatic impairment
- Hypersensitivity to fluorinated anaesthetics or a history of possible adverse reactions in either the patients or relatives (malignant hyperthermia)
- Concomitant use of nephrotoxic medications such as gentamicin or tetracycline
- Tramadol only
- Any allergies to tramadol or codeine
- Any history of seizures, epilepsy
- Patients who are taking anti-depressants
Key Trial Info
Start Date :
February 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2015
Estimated Enrollment :
380 Patients enrolled
Trial Details
Trial ID
NCT01887951
Start Date
February 1 2014
End Date
October 1 2015
Last Update
February 10 2017
Active Locations (1)
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1
Singapore Civil Defence Force
Singapore, Singapore