Status:
WITHDRAWN
Influence of tDCS on Cortical Plasticity in Healthy Older Adults
Lead Sponsor:
Charite University, Berlin, Germany
Conditions:
Healthy Older Adults
Eligibility:
All Genders
50-80 years
Phase:
NA
Brief Summary
The aim of this study is to investigate whether the anodal transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) in healthy older adults leads to an increase in cortical pl...
Eligibility Criteria
Inclusion
- right-handed according to the Oldfield Händigkeits inventory (lateralization index \>70)(1971)
- no obvious cognitive impairment (MMSE\>26, Demtect\>13)
- age between 50 and 80 years
Exclusion
- Severe neurological / psychiatric or pre-existing internist conditions because additional cognitive deficits are expected
- Epilepsy, epileptic seizure in medical history
- Cognitive deficit (MMSE \<20)
- Depressive episode (Beck Depression Inventory (BDI) \> 12)
- intake of centrally active drugs \<3 months , particularly acetylcholinesterase inhibitors
- Pregnancy
- Pacemaker (contraindication for MRI)
- Other metal parts in the body (contraindication for MRI)
Key Trial Info
Start Date :
May 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2017
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01888055
Start Date
May 1 2013
End Date
December 1 2017
Last Update
May 14 2021
Active Locations (1)
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1
Klinik und Poliklinik für Neurologie, Charité Universitätsmedizin Berlin
Berlin, Germany, 10117