Status:
COMPLETED
Preimplantation Genetic Diagnosis (PGD) With Gonadotropin-releasing Hormone (GnRH) Agonist Versus Antagonist
Lead Sponsor:
Universitair Ziekenhuis Brussel
Conditions:
Reproductive Endocrinology
Fertility
Eligibility:
FEMALE
18-39 years
Phase:
PHASE4
Brief Summary
The aim of our study is to define the optimal ovarian stimulation protocol concerning PGD and for this reason we plan a randomized controlled trial (RCT) comparing gonadotropin-releasing hormone (GnRH...
Detailed Description
Patients will be randomized at the outpatient clinic in two groups.
Eligibility Criteria
Inclusion
- ≤ 39 years the day of oocyte retrieval
- BMI ≤ 29
- cycle rank 1
- menstrual cycle 25-36 days
- PGD or preimplantation genetic screening (PGS) requested
- ICSI
- Single embryo transfer (SET) on day 5
Exclusion
- Polycystic Ovary Syndrome (PCOS) (according Rotterdam criteria)
- Hormonal disturbances
- Endometriosis grade III and IV
Key Trial Info
Start Date :
September 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2013
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT01888744
Start Date
September 1 2010
End Date
June 1 2013
Last Update
June 28 2013
Active Locations (1)
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1
Centre for Reproductive Medicine
Brussels, Belgium, 1090