Status:
COMPLETED
Effect of a Grape Seed Extract (GSE) on Insulin Resistance
Lead Sponsor:
University of California, Davis
Collaborating Sponsors:
Illinois Institute of Technology
Conditions:
Metabolic Syndrome
Eligibility:
All Genders
20-70 years
Phase:
NA
Brief Summary
In people with the metabolic syndrome, the investigators hypothesize that administration of a single 300 mg dose of a grape seed extract (GSE) will reduce insulin resistance (how well cells in the bod...
Detailed Description
In people with the metabolic syndrome, the investigators hypothesize that administration of a single 300 mg dose of a grape seed extract (GSE) will reduce insulin resistance (how well cells in the bod...
Eligibility Criteria
Inclusion
- Inclusion Criteria
- Metabolic Syndrome, based on subject meeting at least 3 of the following criteria:
- Abdominal obesity with waist circumference \> 40 inches in men or \> 35 inches in women,
- Pre-hypertension with blood pressure \> 135/85,
- Fasting blood glucose levels above 110 mg/dl,
- Plasma triglyceride levels in excess of 150 mg/dl,
- HDL levels below 40 mg/dl in men or 50 mg/dl in women.
- Exclusion Criteria:
- Any known systemic disease,
- Diabetes,
- Alcohol consumption \> 1-2 drinks/week,
- Taking any medications or supplements that will affect metabolism, their ability to exercise or oxidative status,
- Smokers,
- Female subjects having abnormal menstrual cycles, taking oral contraceptives, pregnant or lactating.
Exclusion
Key Trial Info
Start Date :
November 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2015
Estimated Enrollment :
19 Patients enrolled
Trial Details
Trial ID
NCT01889368
Start Date
November 1 2012
End Date
March 1 2015
Last Update
June 27 2017
Active Locations (1)
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1
VA Hospital, Mather
Mather, California, United States, 95655