Status:
WITHDRAWN
Clinical Characteristics of Dementias That Occur Remotely After Traumatic Brain Injury in Retired Military Personnel
Lead Sponsor:
Uniformed Services University of the Health Sciences
Collaborating Sponsors:
University of California, San Francisco
Conditions:
Dementia
Traumatic Brain Injury (TBI)
Eligibility:
All Genders
50-95 years
Brief Summary
The objective of this study is to measure the frequency and clinical types of mild cognitive impairment (MCI) or dementia that occur among up to 150 military retirees with and without a history of tra...
Detailed Description
75 participants with a history of TBI will be the cases (exposed) group. A control group of 75 retirement home residents without a history of TBI who are age-matched to the cases will also be recruite...
Eligibility Criteria
Inclusion
- Cases (with a history of TBI):
- Ages 50-95 years
- History of traumatic brain injury of sufficient severity to have resulted in medical attention (ascertained via the Ohio State University TBI Identification Questionnaire-OSU TBI-ID, and based on DoD/VA criteria)
- Residence in AFRH-Washington D.C. or the Veterans Home of California-Yountville
- MMSE score ≥ 20
- Capacity to provide consent to participate in research (assessment made by study physician)
- Ability to read and write English
- Controls (without a history of TBI):
- Ages 50-95 years
- No history of traumatic brain injury of sufficient severity to have resulted in medical attention (ascertained via the Ohio State University TBI Identification Questionnaire-OSU TBI-ID)
- Residence in AFRH-Washington or the Veterans Home of California-Yountville
- MMSE score ≥ 20
- Capacity to provide consent or assent to participate in research
- Ability to read and write English -
Exclusion
- Cases (with a history of TBI):
- History of penetrating brain injury
- History of disabling neurological or psychiatric condition such as epilepsy (besides posttraumatic epilepsy), multiple sclerosis, cortical stroke, hypoxic-ischemic encephalopathy, encephalitis, or schizophrenia
- Controls (without a history of TBI):
- History of disabling neurological or psychiatric condition such as epilepsy, multiple sclerosis, cortical stroke, hypoxic-ischemic encephalopathy, encephalitis, or schizophrenia
- \-
Key Trial Info
Start Date :
July 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2016
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01891383
Start Date
July 1 2013
End Date
August 1 2016
Last Update
January 18 2019
Active Locations (2)
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1
California Veterans Home-Yountville
Yountville, California, United States, 94599
2
Armed Forces Retirement Home
Washington D.C., District of Columbia, United States, 20011-8400