Status:
COMPLETED
Evaluating Two Types of Cognitive Training in Veterans With Schizophrenia
Lead Sponsor:
VA Office of Research and Development
Conditions:
Schizophrenia
Eligibility:
All Genders
25-65 years
Phase:
NA
Brief Summary
Cognitive dysfunction is a major contributor to the poor community outcome of individuals with schizophrenia. Developing more effective cognitive remediation interventions is imperative to improve the...
Detailed Description
Schizophrenia is a disorder that affects both higher-level neurocognitive operations (e.g., verbal memory, executive functioning) and lower-level perceptual processes (e.g., auditory processing). Thes...
Eligibility Criteria
Inclusion
- Veterans with a Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) diagnosis of schizophrenia or schizoaffective disorder
- Between 25 and 65 years of age
- Estimated premorbid inteIligence quotient (IQ) \> 70 (based on reading ability)
- Understand spoken English sufficiently to comprehend the consent form
- Clinically stable (i.e., no inpatient hospitalization in the 3 months, no changes in psychiatric medications in the 6 weeks, and no changes in housing in the 2 months, prior to enrollment)
Exclusion
- Documented history of mental retardation or severe learning disability
- Clinically significant neurological disease as determined by medical history (e.g., epilepsy, stroke)
- History of serious head injury with loss of consciousness greater than 1 hour and concomitant neuropsychological sequelae
- Meeting DSM-IV criteria for drug or alcohol dependence during the 6 months, or abuse during the month preceding study enrollment
Key Trial Info
Start Date :
November 21 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2018
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT01891721
Start Date
November 21 2013
End Date
June 30 2018
Last Update
August 14 2019
Active Locations (2)
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1
Local Board and Care Facilities
Los Angeles, California, United States, 90073
2
VA Greater Los Angeles Healthcare System, West Los Angeles, CA
West Los Angeles, California, United States, 90073