Status:

COMPLETED

Reducing Agitation in People With Dementia: the Customized Activity Trial

Lead Sponsor:

Johns Hopkins University

Collaborating Sponsors:

National Institute on Aging (NIA)

Conditions:

Dementia

Eligibility:

All Genders

21+ years

Phase:

NA

Brief Summary

Over 5 million Americans have Alzheimer's disease or a related dementia, a progressive and irreversible neurodegenerative condition, affecting also close to 15 million family caregivers (CG). A hallma...

Detailed Description

Over 5 million Americans have Alzheimer's disease or a related dementia, a progressive and irreversible neurodegenerative condition, affecting also close to 15 million family caregivers (CG). A hallma...

Eligibility Criteria

Inclusion

  • Inclusion criteria pertain to both the person with dementia (PwD) and the caregiver (CG) such that if either is eligible but the other is not, the dyad is not enrolled.
  • PwD and caregiver are English speaking
  • Diagnosed with probable dementia
  • PwD is able to participate in at least 2 activities of daily living (bathing, dressing, grooming, toileting, transferring from bed to chair)
  • Person with dementia exhibits agitated or aggressive behaviors
  • If PwD is on a psychotropic medication he/she must be on a stable dose for at least 60 days
  • CG is at least 21 years old
  • CG lives with or within 5 miles of the person with dementia
  • CG is accessible by telephone to schedule interviews and sessions
  • CG is planning to live in the area for at least 6 months
  • If the CG is on a psychotropic medication he/she must be on a stable dose for at least 60 days

Exclusion

  • Exclusion criteria pertain to both the person with dementia and the caregiver such that if either is eligible but the other is not, the dyad is not enrolled.
  • PwD has a history of schizophrenia or bipolar disorder
  • Dementia is secondary to probable head trauma
  • PwD is not responsive to environment (e.g., unable to understand short commands or recognize a person coming in/out of the room).
  • the CG is currently involved in another clinical trial of psychosocial or educational interventions
  • the CG is planning to place PwD in a nursing home within 6 months.
  • dyads will be excluded if either CG or PwD: 1) has a terminal illness with life expectancy \< 6 months, 2) is in active treatment for cancer, or 3) has had \> 3 acute medical hospitalizations in past year.

Key Trial Info

Start Date :

November 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 23 2017

Estimated Enrollment :

250 Patients enrolled

Trial Details

Trial ID

NCT01892579

Start Date

November 1 2013

End Date

November 23 2017

Last Update

September 23 2019

Active Locations (1)

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Johns Hopkins University School of Nursing, Center for Innovative Care in Aging

Baltimore, Maryland, United States, 21205