Status:

COMPLETED

MPA Pharmacokinetics in Renal Transplantation

Lead Sponsor:

University of Sao Paulo General Hospital

Conditions:

Kidney Transplantation Recipients

Eligibility:

All Genders

18-65 years

Brief Summary

Adequate exposure to mycophenolic acid (MPA) is associated with better outcomes in kidney transplantation. This study evaluated repeated, MPA pharmacokinetics (MPA-PK) according to post-transplant tim...

Eligibility Criteria

Inclusion

  • Male and female patients aged 18-65 years, recipients of a non-HLA identical kidney allograft who presented a PRA \< 50% were eligible for the MoDIFY trial. Subjects were excluded if they received a non-renal organ, had current history of alcohol or illicit drug abuse, had liver enzymes more than two times the upper normal limit or received induction with anti-lymphocyte preparations.

Exclusion

    Key Trial Info

    Start Date :

    September 1 2002

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    June 1 2005

    Estimated Enrollment :

    52 Patients enrolled

    Trial Details

    Trial ID

    NCT01892761

    Start Date

    September 1 2002

    End Date

    June 1 2005

    Last Update

    July 4 2013

    Active Locations (1)

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    Renal Transplantation Service

    São Paulo, São Paulo, Brazil, 05403-900