Status:

TERMINATED

Placebo-Controlled Therapeutic Trial for the Prevention of Lymphedema

Lead Sponsor:

Stanford University

Conditions:

Lymphedema

Unspecified Adult Solid Tumor, Protocol Specific

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

This randomized clinical trial studies an investigational drug in preventing lymphedema in patients at high risk after undergoing axillary lymph node dissection. The study drug may prevent lymphedema ...

Detailed Description

PRIMARY OBJECTIVES: I. To evaluate the efficacy of study drug in improving chronic lymphedema while further elucidating the role of inflammatory and lymphangiogenic processes in the pathogenesis of t...

Eligibility Criteria

Inclusion

  • Axillary lymph node dissection within the preceding 12 months

Exclusion

  • Patients with active cancer
  • Patients with lymphedema
  • Infection or bleeding tendency
  • Patients with medical contraindications to nonsteroidal anti-inflammatory drugs (NSAIDs), including history of allergies, know gastrointestinal intolerance
  • Other serious systemic illness (e.g., renal failure, hepatic dysfunction, congestive heart failure, neurological or psychological impairment) that would impair the patients' ability to participate
  • Persons not competent to consent
  • Patients on aspirin therapy
  • Minors (\< 18 years of age)
  • Pregnant and/or lactating women
  • Males

Key Trial Info

Start Date :

April 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2015

Estimated Enrollment :

14 Patients enrolled

Trial Details

Trial ID

NCT01893879

Start Date

April 1 2014

End Date

April 1 2015

Last Update

May 18 2017

Active Locations (1)

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1

Stanford University Hospitals and Clinics

Stanford, California, United States, 94305