Status:

COMPLETED

Dietary Effects on Circulating Lipoprotein-associated Phospholipase A2 (Lp-PLA2) Activity and Enzyme Activity in Peripheral Blood Mononuclear Cells (PBMCs) in Patients With Prediabetes or Newly Diagnosed Type 2 Diabetes

Lead Sponsor:

Yonsei University

Conditions:

Impaired Fasting Glucose

Newly Diagnosed Type 2 Diabetes

Eligibility:

All Genders

39-74 years

Phase:

NA

Brief Summary

We determined the effects of dietary intervention (replacement of refined rice with whole grains and legumes and a high intake of vegetables) on circulating Lp-PLA2 activity and enzyme activity in per...

Detailed Description

Ninety-nine patients with impaired fasting glucose (IFG), impaired glucose tolerance (IGT) or newly-diagnosed type 2 diabetes were randomly assigned to either a control group (usual diet with refined ...

Eligibility Criteria

Inclusion

  • Subjects who were in in impaired fasting glucose (IFG, 100≤ fasting glucose \<126 mg/dL)
  • or newly diagnosed type 2 diabetes (fasting glucose ≥126 mg/dL)

Exclusion

  • current and/or past history of cardiovascular disease including angina
  • liver or kidney dysfunction
  • thyroid or pituitary disease
  • unstable weight loss/gain (≥2 kg) over the previous 12 months
  • pregnancy or lactation
  • taking medications or supplements

Key Trial Info

Start Date :

January 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2012

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT01895387

Start Date

January 1 2012

End Date

October 1 2012

Last Update

July 10 2013

Active Locations (1)

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Yonsei University

Seoul, South Korea