Status:
TERMINATED
Performance of IGRAs for TB Infection Diagnosis in Elderly
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Ageing
Tuberculosis
Eligibility:
All Genders
75+ years
Brief Summary
Background: Diagnosis and screening for latent tuberculosis in old patients is of special interest in regards of the morbidity-mortality of this disease in that context. TB-infection diagnosis based ...
Detailed Description
In vitro Interferon Gamma releasing Assay (IGRA) are recommended for LTBI screening as or instead of TST, but there accuracy in those old patients are not known: as immune responses are impaired in el...
Eligibility Criteria
Inclusion
- Age \> 75 years
- Consent signed
- hospitalized patient with start treatment of Tuberculosis disease
- French social right
Exclusion
- Tuberculosis disease treatment since 7 days
- No 3 months follow-up possible
- Immunosuppression
Key Trial Info
Start Date :
July 17 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 17 2019
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT01895582
Start Date
July 17 2013
End Date
March 17 2019
Last Update
May 28 2021
Active Locations (3)
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1
Service de médecine interne
Bondy, France, 93143
2
Servive de Médecine Interne (Pr S. Herson)
Paris, France, 75013
3
Service de Médecine Interne, Diabete et Maladies Métaboliques
Strasbourg, France, 67000