Status:
COMPLETED
Renal and Hepatic Clearance Following High-Dose Methotrexate in Childhood ALL
Lead Sponsor:
Rigshospitalet, Denmark
Collaborating Sponsors:
Danish Cancer Society
Conditions:
Lymphoblastic Leukemia, Acute, Childhood
Eligibility:
All Genders
Up to 19 years
Brief Summary
High-dose methotrexate therapy (HDMTX) is an important part of treatment of childhood acute lymphoblastic leukemia (ALL). HDMTX would be improved substantially if it were possible to predict the clear...
Detailed Description
Due to optimization of dosing and intensity of conventional anticancer drugs combined with early risk group classification and clinical trials the cure rates of childhood acute lymphoblastic leukemia ...
Eligibility Criteria
Inclusion
- Admitted to Rigshospitalet
- Diagnosed with ALL
- Receiving high dose MTX
Exclusion
- Using diaper (only exclusion criteria for the study part concerning urine collection)
- Above 19 years of age
Key Trial Info
Start Date :
March 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2013
Estimated Enrollment :
43 Patients enrolled
Trial Details
Trial ID
NCT01896752
Start Date
March 1 2011
End Date
January 1 2013
Last Update
July 16 2013
Active Locations (1)
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1
Department of Pediatrics, Rigshospitalet
Copenhagen, Denmark, 2100