Status:
COMPLETED
Stimulation of Diet-Induced Thermogenesis by Cold-Exposure
Lead Sponsor:
Pennington Biomedical Research Center
Conditions:
Thermogenesis
Brown Adipose Tissue
Eligibility:
MALE
18-35 years
Phase:
NA
Brief Summary
Human fat tissue is essentially white fat, the main function of which is to store excess energy intake, and to release it when necessary. Brown fat is far less abundant and is present in the body to b...
Detailed Description
This study will have 3 phases: Phase 1: baseline testing. This phase takes place at the beginning of the study to establish several physical, physiological and metabolic studies and includes measures...
Eligibility Criteria
Inclusion
- Men between the ages of 18-35 years, inclusive
- Body mass index (BMI) between 18.5 and 25.0 kg/m2, inclusive, with a stable weight (\<2kg variation) within the past 3-6 months
- Non smokers
- On no medication or recreational drugs
- Healthy as assessed by a standard self-reported screening health questionnaire
- Provide written informed consent
Exclusion
- Smokers
- Individuals taking any medications
- Individuals taking any stimulants
- Individuals taking beta-blockers
- Individuals with diabetes or impaired fasting glucose as defined by theADA criteria, i.e. fasting plasma glucose concentration ≥ 5.6 mmol/L (100 mg/dl).
- Individuals with chronic alcohol consumption (\> 3 drinks per day) or drug abuse
- Individuals unable to abstain from caffeinated beverage or alcohol the days of study
- Individuals with pacemakers or defibrillators
- Individuals with history of heart disease or history of stroke
- Individuals having a significant recent loss or gain of weight
- Individuals involved in regular (\> 3 times per week), intense competitive sporting activities.
- Individuals involved in intensive exercise activity.
Key Trial Info
Start Date :
November 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2012
Estimated Enrollment :
9 Patients enrolled
Trial Details
Trial ID
NCT01898949
Start Date
November 1 2010
End Date
May 1 2012
Last Update
January 8 2016
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70808