Status:

COMPLETED

ALL-Active: A Family-Based Lifestyle Program for Pediatric Acute Leukemia Patients

Lead Sponsor:

Vanderbilt-Ingram Cancer Center

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Childhood Acute Lymphoblastic Leukemia in Remission

Eligibility:

All Genders

2-18 years

Phase:

NA

Brief Summary

This randomized pilot phase II trial studies how well nutritional intervention and exercise intervention works in preventing metabolic syndrome in younger patients with acute lymphoblastic leukemia. N...

Detailed Description

PRIMARY OBJECTIVES: I. To evaluate feasibility, adherence, completion rates and participant satisfaction associated with a family based lifestyle intervention for overweight pediatric acute lymphobla...

Eligibility Criteria

Inclusion

  • Diagnosis of pre-B cell or T cell ALL and in continuous first remission; at least 3 months into maintenance therapy with at least 7 months remaining before therapy completion
  • English speaking patient and primary caregiver
  • BMI \>= 75th percentile at time of study enrollment; (patients \>= 75th percentile were selected as they were the group in our preliminary data that had a high risk of becoming overweight during maintenance therapy)
  • Provision of informed consent by primary caregiver

Exclusion

  • Any physical or mental limitation that would prevent participation in study activities (Including but not limited to grade 4 neuropathy or inability to ambulate)
  • As this is intended to be a family-based intervention, all family members will be invited to participate, including those living in more than one household, however endpoints will only be assessed formally in the patient and identified primary caregiver; siblings are not required for participation.

Key Trial Info

Start Date :

May 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2015

Estimated Enrollment :

33 Patients enrolled

Trial Details

Trial ID

NCT01901367

Start Date

May 1 2013

End Date

September 1 2015

Last Update

May 8 2018

Active Locations (1)

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Vanderbilt University

Nashville, Tennessee, United States, 37232