Status:
COMPLETED
Efficacy of Intravenous Ibuprofen Compared to Intravenous Ketorolac for Pain Control Following Arthroscopic Knee Surgery
Lead Sponsor:
Cumberland Pharmaceuticals
Conditions:
Pain
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to assess the efficacy of intravenous ibuprofen compared to ketorolac for the treatment of postoperative pain as measured by patient pain intensity (Visual Analog Scale, V...
Eligibility Criteria
Inclusion
- Patients scheduled for knee arthroscopy
Exclusion
- Inadequate IV access.
- History of allergy or hypersensitivity to any component of ibuprofen, ketorolac, aspirin (or aspirin related products), non-steroidal anti-inflammatory drugs (NSAIDs), opioids or cyclooxygenase-2 (COX-2) inhibitors.
- Less than 18 years of age.
- Use of analgesics less than 8 hours prior to surgery.
- Patients with active, clinically significant anemia.
- History or evidence of asthma or heart failure.
- Pregnant.
- Recent history of chronic opioid use.
- Concomitant use of probenecid.
- Inability to understand the requirements of the study, be willing to provide written informed consent (as evidenced by signature on an informed consent document approved by an Institutional Review Board \[IRB\]), and agree to abide by the study restrictions and to return for the required assessments.
- Refusal to provide written authorization for use and disclosure of protected health information.
Key Trial Info
Start Date :
July 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2014
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT01901393
Start Date
July 1 2013
End Date
August 1 2014
Last Update
March 14 2016
Active Locations (4)
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1
Shrock Orthopedic Research
Fort Lauderdale, Florida, United States, 33316
2
Rush University Medical Center
Chicago, Illinois, United States, 60612
3
North Mississippi Sports Medicine & Orthopaedic Clinic
Tupelo, Mississippi, United States, 38801
4
The Ohio State University Vexner Medical Center
Columbus, Ohio, United States, 43210