Status:

COMPLETED

Nitroglycerin Infusion During Cardiac Surgery

Lead Sponsor:

Tri-Service General Hospital

Conditions:

Lactic Acidosis

Blood Glucose, High

Eligibility:

All Genders

20-85 years

Phase:

NA

Brief Summary

Hypothermic cardiopulmonary bypass results in peripheral vasoconstriction and heparin trapping. Hypoperfusion and ischemic-reperfusion injury are associated with systemic inflammatory response, while ...

Detailed Description

A randomized clinical trial in a tertiary academic center in patients with cardiac surgery, to receive either nitroglycerin infusion dose of 0-0.1 mcg/kg/min, or 1-5 mcg/kg/min during rewarming in car...

Eligibility Criteria

Inclusion

  • elective cardiac surgery

Exclusion

  • heart failure, respiratory failure, asthma attack, uremia, normothermic bypass.

Key Trial Info

Start Date :

July 8 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 8 2017

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT01901419

Start Date

July 8 2013

End Date

June 8 2017

Last Update

November 24 2020

Active Locations (1)

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Tri-Service General Hospital

Taipei, Taiwan, 114