Status:
COMPLETED
Study to Investigate Benefits of Weight Loss in Young Adults and Adolescents
Lead Sponsor:
Yale University
Collaborating Sponsors:
National Institutes of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Conditions:
Obesity
Insulin Resistance
Eligibility:
FEMALE
16-32 years
Phase:
NA
Brief Summary
The purpose of this study is to investigate the changes in subcutaneous adipocyte size, number and gene expression after weight loss and to assess whether those changes contribute to decreases in ecto...
Detailed Description
There are no studies in young women that have prospectively studied changes in fat cell size, gene expression and insulin sensitivity during the transition from overweight/obese to normal weight. Our ...
Eligibility Criteria
Inclusion
- Women ages 16-32
Exclusion
- They will not be on any medications that are known to alter glucose or insulin metabolism, such as oral steroids, or certain psychiatric medications, such as Xeleca, Lithium and Paxil. Patients on diuretics will be excluded.
Key Trial Info
Start Date :
May 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2018
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT01901978
Start Date
May 1 2011
End Date
August 1 2018
Last Update
March 2 2020
Active Locations (1)
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1
Yale University
New Haven, Connecticut, United States, 06520