Status:
COMPLETED
The Effects of Anti-oxidants on Clinical Outcomes and Radiological Features of Chronic Spinal Cord Injury: A Pilot Study
Lead Sponsor:
McMaster University
Conditions:
Spinal Cord Injury
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study will enroll 10 adults with a chronic spinal cord injury. The investigators will image their damaged motor tracts using MRI tractography scanning, and the investigators will formally assess ...
Detailed Description
This is an open label prospective pilot study. The results of this study will assist the researchers in organizing a larger study. The objective of the study is to determine if treatment with over the...
Eligibility Criteria
Inclusion
- Age greater than 18 years
- Spinal cord injury at least on year prior to enrollment
- Able to swallow pills at described dose and by mouth
- Able to provide informed consent
- Able to travel to Hamilton General Hospital for initial and follow-up MRI tractography studies
- Willing to attend monthly meetings with investigators
Exclusion
- Contraindication to MRI scanning such as metal in the body, pacemaker, implanted nerve stimulator, or claustrophobia.
- Concomitant neurological condition such as stroke, acquired brain injury, peripheral nerve injury
- Pressure ulcer at time of enrollment into study
- Uncontrolled autonomic dysreflexia
- Current usage of anticoagulants
- Allergy to Selenium or Vitamin E, or present supplementation of both/ either nutrient at study dosage levels.
- History of Cardiovascular disease (heart attack)
- Any planned or anticipated surgical treatment for spinal cord injury
Key Trial Info
Start Date :
October 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2016
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT01904591
Start Date
October 1 2013
End Date
July 1 2016
Last Update
September 13 2016
Active Locations (1)
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1
Regional Rehabilitation Centre At Hamilton General Hospital
Hamilton, Ontario, Canada, L8L 0A4