Status:
COMPLETED
Acute Renal Failure Post Liver Transplantation
Lead Sponsor:
Baylor Research Institute
Conditions:
Acute Renal Failure
Eligibility:
All Genders
18-71 years
Phase:
NA
Brief Summary
Trial to test the effect of administering N-acetylcysteine on cytokines and markers of oxidant stress and the incidence of acute renal failure post liver tranplant
Detailed Description
1. To determine levels of pro-inflammatory cytokines and oxidative stress markers in liver transplant patients during post-transplant period 2. To correlate changes in pro-inflammatory cytokines and m...
Eligibility Criteria
Inclusion
- First liver transplant
- Normal renal function before transplantation \[serum creatinine ≤ 1.5 mg / dl\]
- No requirements for dialysis before transplantation
- Age greater than 18 years
Exclusion
- Re-transplant
- Renal dysfunction i.e. serum creatinine \> 1.5 mg/dl
- Need for dialysis before transplantation
- Presence of Hepatorenal or Hepatopulmonary syndrome\*
- Combined liver and kidney transplant
- Peptic ulcer disease
- Pregnancy
Key Trial Info
Start Date :
July 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2014
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01907061
Start Date
July 1 2007
End Date
July 1 2014
Last Update
February 21 2020
Active Locations (1)
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1
Annette C. and Harold C. Simmons Tranplant Institute at Baylor Medical Center Dallas
Dallas, Texas, United States, 75246