Status:
COMPLETED
Enhancing the Effectiveness of Electroconvulsive Therapy in Severe Depression
Lead Sponsor:
St Patrick's Hospital, Ireland
Collaborating Sponsors:
Health Research Board, Ireland
Conditions:
Depression
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Electroconvulsive therapy (ECT) is the most powerful antidepressant treatment available and is often life-saving. There are concerns, however, that standard bitemporal ECT (the most commonly used form...
Detailed Description
The study is a two-group parallel design randomised controlled non-inferiority trial and has been registered (ISRCTN23577151). Consented patients with major depressive disorder (DSM-IV) will be random...
Eligibility Criteria
Inclusion
- Patients ≥18 years diagnosed with major depressive episode (DSM-IV) and referred for ECT
Exclusion
- Any condition rendering patients medically unfit for general anaesthesia or ECT; treatment with ECT in previous six months; dementia or other Axis 1 diagnosis; alcohol/other substance abuse in previous six months; inability/refusal to consent.
Key Trial Info
Start Date :
May 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2015
Estimated Enrollment :
138 Patients enrolled
Trial Details
Trial ID
NCT01907217
Start Date
May 1 2008
End Date
April 1 2015
Last Update
November 14 2018
Active Locations (1)
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1
St Patrick's University Hospital
Dublin, Ireland, 8