Status:
COMPLETED
A Trial of EBUS-TBNA Versus Conventional TBNA in Diagnosis of Sarcoidosis
Lead Sponsor:
Post Graduate Institute of Medical Education and Research, Chandigarh
Conditions:
Sarcoidosis
Eligibility:
All Genders
15-75 years
Phase:
NA
Brief Summary
The investigators hypothesize that conventional or EBUS-TBNA will have equal efficiency in diagnosing sarcoidosis when performed in conjunction with endobronchial and transbronchial lung biopsy.
Detailed Description
Diagnostic procedures like transbronchial lung biopsy (TBLB), transbronchial needle aspiration (TBNA) and endobronchial biopsy (EBB) are routinely used to obtain pathological confirmation of pulmonary...
Eligibility Criteria
Inclusion
- Consecutive patients presenting with clinicoradiological features suggestive of sarcoidosis and an indication for transbronchial needle aspiration
Exclusion
- Pregnancy
- Hypoxemia (SpO2 \<90%) on room air
- Poor lung function (forced expiratory volume in first second \[FEV1\] \<1L)
- Patients with deranged clotting profile (prothrombin time \>3 seconds above control; activated partial thromboplastin time \>10 seconds above control, platelet count \<50000/µL)
- Patients already initiated on glucocorticoids
- Diagnosis of sarcoidosis possible on minimally invasive techniques such as skin biopsy or peripheral lymph node biopsy and failure to provide informed consent
Key Trial Info
Start Date :
November 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT01908868
Start Date
November 1 2011
End Date
December 1 2012
Last Update
December 30 2014
Active Locations (1)
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1
Chest Clinic, PGIMER
Chandigarh, India, 160012