Status:
COMPLETED
The Effects of Statin on Postoperative Renal Function in Valvular Heart Surgery: a Randomized, Placebo-controlled Study
Lead Sponsor:
Yonsei University
Conditions:
Acute Kidney Injury
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
The aim of this study is to examine the association between preoperative statin treatment and the incidence of postoperative acute kidney injury(AKI) in patients undergoing valvular heart surgery.
Eligibility Criteria
Inclusion
- \- patients over the age of 20 scheduled for valvular heart surgery
Exclusion
- Current statin use
- Left ventricular ejection fraction \< 30%
- Preexisting congestive heart failure
- Severe coronary artery disease
- Hemodynamically unstable arrhythmia
- Cardiogenic shock during perioperative period
- Ventricular assist device
- Severe renal dysfunction (eGFR \< 15 ml/min per 1.73 m2)
- History of liver disease or elevated serum transaminases
- History of rhabdomyolysis or elevated creatinine kinase
Key Trial Info
Start Date :
July 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 21 2015
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT01909739
Start Date
July 1 2013
End Date
August 21 2015
Last Update
March 28 2019
Active Locations (1)
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1
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine
Seoul, South Korea, 120-752