Status:
UNKNOWN
Combined Use of Etomidate and Propofol in Painless Gastroscopy.
Lead Sponsor:
Jiangsu Nhwa Pharmaceutical Co., Ltd.
Conditions:
Safety of Gastroscopy
Eligibility:
All Genders
45-75 years
Phase:
PHASE4
Brief Summary
Gastroscopy, as a conventional examination for gastrointestinal tract disease, plays a very important role especially in early diagnosis and differential diagnosis of esophageal and gastric carcinoma....
Detailed Description
There are 6 centers for this trial: General Hospital of Chinese People's Liberation Army, Chaoyang Hospital Attached to the Capital Medical University, The Second Affiliated Hospital of Harbin Medical...
Eligibility Criteria
Inclusion
- Preparing to take gastroscopy;
- Age:between 45 to 75 years old (middle-aged group: 45\~59 years old; elderly group: 60\~75 years old; the percentage of middle-aged group and elderly group are 60% and 40%, respectively);
- BMI: between 18 to 25 kg/m2;
- ASA classification: grade Ⅰ\~Ⅱ.
Exclusion
- Blood pressure before operation: \>180 mm Hg or \<90 mm Hg;
- ECG before operation: \<50 beats per min;
- HGB before operation: \<90 g/L;
- Infected with respiratory inflammation and not cured within 2 weeks;
- Sever heart, brain, pulmonary, heptic, renal diseases or diabetes;
- History of difficult airway or abnormal recovery from anesthesia before or difficult airway is predicted to occur ;
- Obvious electrolyte disturbance such as hyperkalemia;
- Treated with immunosuppressants such as hormones for a long time or prior inhibition of the adrenal cortex;
- Allergic to emulsion or opioids;
- Concomitant other sedatives or analgesics (including injectable or oral administration of treatment related to Chinese Traditional Patent Medicines);
- Suspected abuse of narcotic analgesics or sedatives;
- Patients for whom it is difficult to cooperate or communicate because of abnormalities of neuromuscular system or mental disorder.
Key Trial Info
Start Date :
August 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2013
Estimated Enrollment :
2450 Patients enrolled
Trial Details
Trial ID
NCT01913054
Start Date
August 1 2013
End Date
December 1 2013
Last Update
December 16 2013
Active Locations (6)
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1
Chaoyang Hospital Attached to the Capital Medical University
Beijing, Beijing Municipality, China, 100020
2
General Hospital of Chinese Air Force
Beijing, Beijing Municipality, China, 100036
3
General Hospital of Chinese People's Liberation Army
Beijing, Beijing Municipality, China, 100853
4
The Second Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, China, 150086