Status:

COMPLETED

Acetyl-L-Carnitine Supplementation During HCV Therapy With Pegylated Interferon-α2b Plus Ribavirin

Lead Sponsor:

University of Catania

Conditions:

Work Productivity and Activity Impairment in Workers With Chronic C Hepatitis

Fatigue in Workers With Chronic C Hepatitis

Eligibility:

All Genders

45-65 years

Phase:

PHASE4

Brief Summary

To assess the effects of Acetyl-L-Carnitine administration on work productivity, daily activity, and fatigue in subjects with chronic hepatitis C treated with Pegylated-Interferon-α2b and Ribavirin.

Eligibility Criteria

Inclusion

  • workers who were 18 years of age or older
  • Workers who were infected by HCV and had a quantifiable serum HCV RNA level (as determined by polimerase chain reaction, COBAS AmpliPrep/COBAS TaqMan - ROCHE)
  • Cirrhotic workers with a Child-Pugh score less than 7

Exclusion

  • workers who had other liver diseases
  • cancer
  • severe jaundice
  • pulmonary and renal chronic diseases,
  • prostatic diseases
  • autoimmune diseases
  • diabetes mellitus
  • decompensated cirrhosis
  • pregnancy
  • cardiopathy
  • hemoglobinopathies
  • hemocromatosis
  • major depression
  • severe psychiatric pathological conditions

Key Trial Info

Start Date :

October 1 1997

Trial Type :

INTERVENTIONAL

End Date :

October 1 1997

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT01913964

Start Date

October 1 1997

End Date

October 1 1997

Last Update

August 1 2013

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