Status:

UNKNOWN

Prevention of Chemotherapy Induced Nausea and Vomiting in Breast Cancer Patients.

Lead Sponsor:

Ottawa Hospital Research Institute

Conditions:

Emesis

Eligibility:

FEMALE

19+ years

Phase:

PHASE4

Brief Summary

For breast cancer patients receiving chemotherapy regimens, the use of a validated emesis (nausea and vomiting) risk calculator will provide superior anti-emetic (nausea and vomiting) control compared...

Eligibility Criteria

Inclusion

  • Newly diagnosed invasive breast cancer (stage I-III)
  • Scheduled to receive neoadjuvant or adjuvant intravenous anthracycline with cyclophosphamide-based chemotherapy;
  • Able to consent and fill study forms

Exclusion

  • Received previous chemotherapy
  • Symptoms of nausea or vomiting at baseline (disease related)
  • On chronic anti-emetic therapy
  • On daily corticosteroids prior to initiation of chemotherapy
  • Allergic to steroids, 5HT3 or NK-1
  • Uncontrolled diabetes
  • Medical or psychiatric illness that would interfere with patients' ability to complete the diary

Key Trial Info

Start Date :

September 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2017

Estimated Enrollment :

323 Patients enrolled

Trial Details

Trial ID

NCT01913990

Start Date

September 1 2011

End Date

December 1 2017

Last Update

January 30 2017

Active Locations (1)

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1

The Ottawa Hospital Cancer Centre

Ottawa, Ontario, Canada, K1H 8L6